high platelet count during pregnancy

Oct 21, 2023

The two types of thrombocytosis are primary thrombocytosis and secondary thrombocytosis: A high platelet count may be found during routine blood work and more tests may be done to diagnose any associated conditions. Even for those of us who are healthy, we need to find a doctor who can help us get through the emotional transitions during pregnancy and beyond. Severe IUGR can lead to intrauterine death. If still worried, I suggest you repeat the blood test for platelets again in 2 weeks. What Is the Outlook for Those With High Platelet Counts? But it also can develop in the first week after childbirth (postpartum preeclampsia). When I was pregnant, I also did some readings on pregnancy complications. It usually occurs during the third trimester of pregnancy. Background: Platelet counts of less than 150,000 per cubic millimeter during uncomplicated pregnancies are described as gestational thrombocytopenia if no alternative cause is identified. Figs. Up to 1 in 5 women who have HELLP syndrome experience it a second time. The interaction between the mean platelet counts in the women with preexisting disorders and the mean platelet counts in the women with uncomplicated pregnancies was not significant (P=0.07), which indicated that the rates of decrease in platelet counts did not differ significantly (Fig. Your provider will keep an eye on your blood pressure and other vital signs to catch problems like HELLP early. In women who have a platelet count of less than 100,000 per cubic millimeter, a cause other than pregnancy or its complications should be considered. Department of Biostatistics and Epidemiology, College of Public Health (J.A.R., J.D.P., D.R.T., S.K.V., J.N.G. A registered nurse with more than 25 years of experience in oncology, labor/delivery, neonatal intensive care, infertility and ophthalmology, Sharon Perkins has also coauthored and edited numerous health books for the Wiley "Dummies" series. In addition, thrombocytopenia in women who have preexisting disorders, such as immune thrombocytopenic purpura, may become more severe during pregnancy.4,11 To understand the course of platelet counts throughout pregnancy, we evaluated platelet counts in women who delivered at the Oklahoma University Medical Center between 2011 and 2014. Maymon R, Strauss S, Vaknin Z, Weinraub Z, Herman A, Gayer G. Normal sonographic values of maternal spleen size throughout pregnancy. Is High White Blood Cells (WBC) Count in Pregnancy Normal? Among women who had one of the other three disorders, 1.4 to 6.0% had platelet counts below 80,000 per cubic millimeter (Table S4B in the Supplementary Appendix). S2C in the Supplementary Appendix), we found that platelet counts of less than 150,000 per cubic millimeter occurred in 39 women (19.8%) at the time of delivery (Table 2); 17 women (8.6%) had platelet counts of less than 80,000 per cubic millimeter (median, 48,000; range, 4000 to 77,000). Preterm delivery, or delivery before 37 weeks of pregnancy, occurs in eight percent of cases of thrombocytosis in pregnancy, according to Anil. It is likely that blood tests or imaging will be done. Pregnancy complications. Blood loss, a lack of dietary iron, pregnancy, and intestinal diseases that affect the absorption . Platelets and pregnancy. However, certain serious conditions, such as HELLP syndrome and preeclampsia, can cause very low platelet counts. FOIA Your healthcare provider will order blood tests are ordered to check your blood count, liver function and kidney function. Boehlen F, Hohlfeld P, Extermann P, Perneger TV, de Moerloose P. Platelet count at term pregnancy: a reappraisal of the threshold. 166: thrombocytopenia in pregnancy. Most women who have essential thrombocythemia have normal, healthy pregnancies. How I treat thrombocytopenia in pregnancy | Blood | American Society of When we evaluated all 10,296 platelet count values measured during pregnancy and at the time of delivery in women with pregnancy-related complications (Fig. We identified 3,039 studies; 46 reporting 30 women with normal pregnancies were included in our analyses. Reference Values For Platelet Count in Pregnancy - Perinatology.com Last reviewed by a Cleveland Clinic medical professional on 05/12/2021. What does it mean if your MPV blood test results are high? Gestational thrombocytopenia is far and away the most common cause of low platelets in pregnancy, accounting for 75 to 80 percent of cases. This article discusses the diagnosis process and treatment options for a high platelet count and any associated underlying conditions. To compare postpartum platelet counts with platelet counts at the time of delivery, we used a paired t-test. Blood Platelets in Pregnancy - Pregnancy, Baby Care HELLP syndrome is a rare pregnancy complication. Among all 15,385 women who had singleton pregnancies, 4760 women had pregnancy-related complications. Severe thrombocytopenia is rare, even in women with pregnancy-related complications. HELLP syndrome is a separate disorder from preeclampsia as patients may not have high blood pressure or proteinuria. During pregnancy, sometimes platelet levels can become too low or too high. Platelet Counts during Pregnancy and in Nonpregnant Women.*. Most of the time, your babys platelet count will be within the normal range a few days after birth. High Platelets During Pregnancy | Healthfully If you have thrombotic thrombocytopenic purpura, you may need treatment for your condition during your pregnancy even if you do not have any symptoms. The increase in platelets usually occurs during acute exacerbations (flare-ups) or when the disease is being undertreated. Among all 15,385 women who had singleton pregnancies, 338 women had preexisting disorders that were associated with thrombocytopenia. These tests may include: A high platelet count may be worrisome if: In general, blood clots tend to be linked to primary thrombocytosis. Platelet activity fluctuates throughout pregnancy and is a normal feature of pregnancy owing to the effects of complex coagulation factors such as thromboxane, collagen and other complex proteins. While some stress is unavoidable during pregnancy, avoiding high-stress situations or learning to manage your stress is a good idea. The normal range for WBC count during pregnancy is between 5,000 and 15,000 cells/mcL (microliter) of blood. Thrombocytopenia in pregnancy. EVU BEEPE on Instagram: "~SAVE A ROSE~ Amber Rose Cookies collect information about your preferences and your devices and are used to make the site work as you expect it to, to understand how you interact with the site, and to show advertisements that are targeted to your interests. What are platelets and why are they important? Platelet counts of less than 80,000 per cubic millimeter for which an alternative cause was not identified occurred in only 5 women (0.1%), none of whom had a platelet count below 62,000 per cubic millimeter. National Library of Medicine doi:10.3399/bjgp20X710957, Manne BK, Denorme F, Middleton EA, et al. This. The mean platelet count during the postpartum period did not differ significantly between the women with uncomplicated pregnancies and the nonpregnant women (P = 0.10). In general, the longer the pregnancy continues, the better the outcome for the newborn. Complications that can be a result of either too high or too low platelet levels include: In most cases, platelet levels can be managed by getting routine medical care during pregnancy. Hellp Syndrome - Preeclampsia If you have a high platelet count, taking some birth control pills can raise your risk of blood clots. All the analyses were performed with the use of SAS software, version 9.4 (SAS Institute). Curtin LR, Mohadjer LK, Dohrmann SM, et al. Mean Platelet Volume (MPV) (Whole Blood) During Pregnancy 2012;4(6):415-23. doi:10.4021/jocmr1125w, Brire JB. 6 A very high platelet count can cause blood clots that can block blood flow to the embryo or fetus, while low platelet counts can cause bleeding. Although gestational thrombocytopenia has been recognized for more than 25 years,1 the course of platelet counts throughout pregnancy and the potential severity of gestational thrombocytopenia have not been defined.4,79 Our data showed that among the women who had uncomplicated pregnancies, the decline in platelet counts began in the first trimester and continued throughout pregnancy, with the nadir occurring at the time of delivery, when 9.9% of the women had platelet counts of less than 150,000 per cubic millimeter. 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event, (https://rarediseases.info.nih.gov/diseases/8528/hellp-syndrome), (https://www.preeclampsia.org/hellp-syndrome). HELLP syndrome is rarely life-threatening. Platelets are blood cells that form clots to stop bleeding. 2019;53(5):523-536. doi:10.1177/1060028018819450, Mounce LT, Hamilton W, Bailey SE. The interaction between the mean platelet count in the women with uncomplicated pregnancies and the mean platelet count in the women with pregnancy-related complications was significant (P = 0.002), which indicated that the rates of decrease in platelet counts differed. An abnormally high number of platelets in pregnancy is far less common than low platelet levels. Sunday PM 4/30/23 | Sunday PM 4/30/23 *We do not own the - Facebook J Med Case Rep. 2009;3:91. doi:10.1186/1752-1947-3-91. In healthy, nonpregnant adult women, one third of all circulating platelets are transiently pooled within the low flow-rate circulation of the splenic sinusoids; an increased spleen size results in more pooling of the platelets and a lower platelet count.17 Therefore, the 50% increase in spleen size that occurs during pregnancy18 would also contribute to a lower platelet count. Abruption usually requires immediate delivery or severe maternal and fetal hemorrhage can occur. EL-elevated liver enzymes (liver function) LP-low platelets counts (platelets help the blood clot) . It is a type of preeclampsia. Please refer to our Privacy Policy to change your cookie settings. Placental abruption, where the placenta separates prematurely from the uterine wall, is also a possible complication of thrombocytosis, according to the Mayo Clinic.